Mankind Divided is set in 2029, two years after Deus Ex: Human Revolution. The Deus Ex series is set in a cyberpunk future rife with secret organizations and conspiracies, including the Illuminati. Before Human Revolution, advances in biotechnology and cybernetics led to the development of "augmentations", artificial organs capable of enhancing human performance. Augmentation requires the use of Neuropozyne, a scarce, expensive immunosuppressive drug which prevents the body from rejecting the augmentation. They also created social divides between "augs", humans who have accepted augmentation technology; and normal humans who are either morally opposed to it, too poor to afford it, or whose bodies actively reject it.
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